The Environmental Impact of Use of Antimicrobials in Animal Husbandry Practices It is amazing and humbling, in equal measure, to see how closely interlinked climate, humans, animals, plants, soil, water and bugs (bacteria, virus, parasites, fungi), and insects are. On this planet, every event, no matter how innocuous, impacts everything else- a domino effect. The...
Emerging Antifungal Resistance and the Need for New Antifungal Drugs Context and Significance of Antifungal Resistance Fungal infections cause a global burden of morbidity and mortality comparable to or exceeding major infectious diseases like malaria, tuberculosis, or HIV. The rise of antifungal resistance exacerbates this problem, threatening current treatment options and patient outcomes. The development...
Decoding AmpC Beta-lactamases: The Evolving Threat of Chromosomal and Plasmid-Mediated Resistance AmpC β-lactamases are a formidable class of enzymes, quietly shaping the future of antibiotic resistance in clinical settings. Understanding their genetic origins and dissemination dynamics is crucial for monitoring and preventing multidrug-resistant infections. Unravelling AmpC: Chromosomal vs. Plasmid-Mediated Genes AmpC β-lactamases are enzymes that...