It is amazing and humbling, in equal measure, to see how closely interlinked climate, humans, animals, plants, soil, water and bugs (bacteria, virus, parasites, fungi), and insects are. On this planet, every event, no matter how innocuous, impacts everything else- a domino effect. The miracle drugs- antibiotics and antifungals have lead to unprecedented boom in agriculture, animal husbandry, fisheries not to mention better human and domesticated animal health. The misery unleashed by microbes was well and truly tamed. Or so it appeared…Now we know every action has a reaction. Less than a hundred years of the revolution in healthcare, agriculture and animal husbandry, the microbes have acquired widespread resistance to the miracle drugs. Three hundred years after the industrial revolution, we have managed to make our planet warmer. A warmer planet provides microbes and insects (eg mosquitoes) a ready niche in places which were earlier inhospitable. Dengue is increasingly being reported in Eastern Europe, USA and Middle East. A warmer earth enables microbes to thrive, which means they mutate faster, develop resistance faster…Melting of the icecaps may unleash new and maybe more drug resistant strains. This image shows how closely everything on earth is interlinked-though it does not do justice.